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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6222 | PFI-1 | PF-6405761,PFI 1,PFI1 | Apoptosis , Epigenetic Reader Domain , Autophagy |
PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay. | |||
T81175 | SETD7-IN-1 | Histone Methyltransferase | |
SETD7-IN-1 (compound 7), a PFI-2 analogue, acts as both a substrate and inhibitor of histone lysine methyltransferase SETD7, exhibiting an inhibitory concentration (IC50) of 0.96 ± 0.10 µM [1]. | |||
T60870 | BRG1-IN-1 | ||
BRG1-IN-1 (Compound 11d) is a potent BRG1 inhibitor with better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhib... |